The Science
The Science
Inside the engine:
The science behind
the longevity OS
Inside the engine:
The science behind
the longevity OS
Inside the engine:
The science behind
the longevity OS
The NU Knowledge graph
Developed over five years by a multidisciplinary team of scientists and doctors, our AI-powered bioinformatics operating system decodes complex biological data to deliver multi-omic health insights, multiple biological age clocks and expert-reviewed, evidence-based recommendations.
The NU Knowledge graph
VO2max
Blood
Wearables
Questionnaires
Body Composition
Age Clocks
17+ Health Insights
Test Deep Dives
Microbiome
Epigenome
Genome
4 Guides
Digital Twin
Integrative analysis of a growing number of biomarkers
Integrative analysis of a growing number of biomarkers
Key biomarkers
Nodes
Relationships
Peer reviewed references
Engine
A tech stack
built for scale
A fully modular, internally developed engine—built from the ground up with proprietary science and technology.
Raw Data
Raw Data
Raw Data
Genome
Gut microbiome
Blood
Epigenome
Physiome
Wearables
Epigenome
Physiome
Wearables
Bioinformatic entities
Bioinformatic entities
Bioinformatic entities
SNPs, variants
Microbial species, Genera, Metabolic pathways
Blood biomarkers, ratios, optimal ranges
Body composition, VO2 max
Sleep, HRV, Activity, Glucose level
Methylation status of CpGs
Body composition, VO2 max
Sleep, HRV, Activity, Glucose level
Methylation status of CpGs
Science engine
Science engine
Science engine
Methylation pathways, PGS scores
Multiomic Age Clocks
Multiomic Risk profiles
Nutrition plans and food rankings
Personalised supplement formulas
Specialised exercise programs
Methylation pathways, PGS scores
Multiomic Age Clocks
Multiomic Risk profiles
Deep Dives
In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

Deep Dives
In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

Deep Dives
In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

Age Clocks
A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

Age Clocks
A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

Health Insights
Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Health Insights
Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Health Plans
Health Plans translate your clients’ most important Health Insights into practical strategies across nutrition, supplements, lifestyle and exercise. Each plan outlines priorities and steps that are easy to follow, edit and adapt.

Health Plans
Health Plans translate your clients’ most important Health Insights into practical strategies across nutrition, supplements, lifestyle and exercise. Each plan outlines priorities and steps that are easy to follow, edit and adapt.

Recommendations
Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Recommendations
Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Age Clocks
A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

Age Clocks
A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

Health Insights
Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Health Insights
Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Health Plans
Health Plans translate your clients’ most important Health Insights into practical strategies across nutrition, supplements, lifestyle and exercise. Each plan outlines priorities and steps that are easy to follow, edit and adapt.

Health Plans
Health Plans translate your clients’ most important Health Insights into practical strategies across nutrition, supplements, lifestyle and exercise. Each plan outlines priorities and steps that are easy to follow, edit and adapt.

Recommendations
Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Recommendations
Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Lifestyle habits
Support clients with science-based evaluations of more than 25 lifestyle habits. Each habit is scored for biological impact, strength of evidence, and effect. Clear guidance on frequency and implementation, informed by the latest research, helps clients build sustainable wellness routines.

Lifestyle habits
Support clients with science-based evaluations of more than 25 lifestyle habits. Each habit is scored for biological impact, strength of evidence, and effect. Clear guidance on frequency and implementation, informed by the latest research, helps clients build sustainable wellness routines.
